Health & Lifestyle

A ‘miracle’ weight problems treatment, or harmful TikTok development adored by Hollywood?

Overhauling eating regimen and adopting an intensive train routine was once the go-to method for anybody seeking to shift the scales.

But now there is a ‘miracle’ treatment which successfully provides the chubby a cheat code — permitting them to drastically drop some weight without having to eat buckets of spinach or work-out till drenched in sweat.

A TikTok-inspired craze has seen semaglutide turn into the world’s, and Hollywood’s, hottest product.

Fans embrace Elon Musk, Jeremy Clarkson and social media sensation Remi Bader, who’ve described its results as ‘genuinely unimaginable’. Kim Kardashian has additionally been rumoured to have taken the drug.

Top Gear host Jeremy Clarkson revealed this month that he was taking Ozempic in a bid to lose weight

When asked in October whether following a healthier diet or hitting the gym was behind his 30lb (13.6kg) weight loss, Elon Musk credited 'fasting' and 'Wegovy'.

Top Gear host Jeremy Clarkson (left) revealed this month that he was taking Ozempic in a bid to drop some weight. When requested in October whether or not following a more healthy eating regimen or hitting the health club was behind his 30lb (13.6kg) weight reduction, Elon Musk (proper) credited ‘fasting’ and ‘Wegovy’

Comedian and TV host Chelsea Handler revealed she took the drug after being prescribed it by her doctor — but said it made her nauseous.

TikTok star Remi Bader revealed that she was prescribed Ozempic by her doctor in 2020 'before it was trendy'

Comedian and TV host Chelsea Handler (left) revealed she took the drug after being prescribed it by her physician — however stated it made her nauseous. TikTok star Remi Bader (proper) revealed that she was prescribed Ozempic by her physician in 2020 ‘earlier than it was stylish’

The surprise drug, branded as Ozempic or Wegovy, is given as an injection straight into the abdomen, thigh or higher arm.

It suppresses starvation by mimicking an appetite-regulating hormone, leaving customers feeling fuller for longer.

But, whereas the planet’s main weight problems specialists settle for its apparent good thing about shedding pounds, they warn it isn’t a magic bullet to remain slim. 

And it could set off disagreeable unwanted side effects, from nausea and diarrhoea to pancreatitis and gallbladder issues.

Confusingly, semaglutide is branded as two separate medicine, each of that are made by Denmark-based pharmaceutical large Novo Nordisk.

Ozempic, which is experiencing a surge in reputation, is focused at sufferers with sort 2 diabetes. It lowers their blood sugar and reduces the chance of coronary heart assaults and strokes amongst those that even have coronary heart illness.

The NHS watchdog accepted Ozempic for folks with sort 2 diabetes in 2019, whereas well being chiefs within the US gave it the inexperienced mild for a similar group in 2017.

Private clinics within the UK can provide sufferers the drug off-label for slightly below £200 monthly, whereas it’s freely accessible within the US.

Novo Nordisk has warned it doesn’t assist off-label prescribing, which may restrict provide for sort 2 diabetes sufferers who’ve been prescribed the treatment.

Its sister drug Wegovy, filled with a barely stronger dose of the surprise chemical, has been accessible for people who find themselves chubby and have not less than one weight-related situation since 2021 within the US and 2022 within the UK.

Wegovy is predicted to turn into accessible beneath a non-public prescription within the UK later this 12 months. It is already broadly accessible within the US.

Thanks to the hype, demand has shot via the roof for its fat-busting results.

There have been shortages of each medicine on account of their surge in reputation, with some UK medical doctors evaluating it to the ‘HRT panic’ seen final 12 months, which led to ladies assembly in carparks to swap treatment when provide dried up.

Semaglutide acts like a hormone referred to as glucagon-like peptide-1 (GLP-1), which targets areas of the mind that regulate urge for food and meals consumption — making customers really feel much less hungry.

It additionally slows down the motion of meals within the intestine, which helps customers keep full for longer. 

Clinical trials present that these taking the drug misplaced as much as 15.3kg (2 stone and 6lbs), on common, over the area of 15 months, in comparison with simply 2.6kg (6lbs) within the placebo group.

Top Gear host Jeremy Clarkson revealed this month that he was taking Ozempic in a bid to drop some weight.

He stated he was launched to the injectable drug after studying that his associates had been taking ‘a brand new Danish drug’ to push back diabetes and ‘when questioned all of them raved about it’. 

The 62-year-old, who has previously tried to slim via consuming more healthy and exercising, described its results as being ‘genuinely unimaginable’. 

When requested in October whether or not following a more healthy eating regimen or hitting the health club was behind his 30lb (13.6kg) weight reduction, Elon Musk credited ‘fasting’ and ‘Wegovy’.

TikTok star Remi Bader revealed that she was prescribed Ozempic by her physician in 2020 ‘earlier than it was stylish’. 

Celebrities including Elon Musk, Jeremy Clarkson and Remi Bader have spoke out about the 'genuinely incredible' Ozempic, which suppresses appetite and leaves users feeling fuller for longer

Celebrities together with Elon Musk, Jeremy Clarkson and Remi Bader have spoke out concerning the ‘genuinely unimaginable’ Ozempic, which suppresses urge for food and leaves customers feeling fuller for longer

Wegovy and Ozempic work by triggering the body to produce a hormone called glucagon-like peptide-1 that is released naturally from the intestines after meals

Wegovy and Ozempic work by triggering the physique to supply a hormone referred to as glucagon-like peptide-1 that’s launched naturally from the intestines after meals

But Ms Bader, who has 2.2million followers on the social media website, instructed the Not Skinny But Not Fat podcast that she placed on ‘double the burden’ she misplaced when she got here off the drug as a result of her binge consuming bought ‘a lot worse’.

Meanwhile, comic and TV host Chelsea Handler revealed she took the drug after being prescribed it by her physician — however stated it made her nauseous.

She instructed Variety: ‘Apparently, it makes you lose your urge for food. But I like having an urge for food. It made me nauseous, and I don’t prefer to be nauseous.’

It can also be rumoured that Kim Kardashian used the drug to slim down for the Meta gala, after shedding 16lbs (7.3kg) in three weeks to suit into Marilyn Monroe’s iconic gown, which she wore to sing ‘Happy Birthday’ to then-President John F. Kennedy in 1962. 

And Khloe Kardashian refuted rumours that she had turned to semaglutide.

As will all medicines, Ozempic just isn’t solely risk-free.

Users generally complain of nausea, constipation and diarrhoea, whereas some additionally undergo from acid reflux disease, fatigue and complain that meals tastes totally different after taking the drug.

It is that this facet impact that some folks credit score for additional aiding their weight reduction — by making their favorite junk meals style dangerous. 

Thyroid most cancers, pancreatitis — when the organ turns into infected — and kidney failure are uncommon however critical unwanted side effects.

Patients have additionally warned of their face showing gaunt, exhausted and outdated — a facet impact that has been labelled ‘Ozempic face’.

Doctors have warned that whereas the drug is an instance of ‘very good science’, it’s ‘not a panacea for everybody’, because it would not work for one in 5 sufferers. 

And whereas it could work within the short-term, some will pile the burden again on — so common train and a nutritious diet are nonetheless wanted.

Kim Kardashian is rumoured to have used Wegovy to rapidly lose weight in order to fit in Marilyn Monroe's famous 'Happy Birthday Mr President' dress at the 2022 Met Gala (pictured)

Kim Kardashian is rumoured to have used Wegovy to quickly drop some weight with a view to slot in Marilyn Monroe’s well-known ‘Happy Birthday Mr President’ gown on the 2022 Met Gala (pictured) 

Dr Simon Cork, a senior lecturer in physiology at Anglia Ruskin University, instructed MailOnline that semaglutide is ‘revolutionary by way of treating weight problems’ and the primary class of medicine to point out ‘important, lengthy lasting weight reduction’.

‘That being stated, there are clear tips as to who needs to be provided these medicine,’ he warned.

‘So far the steering is that these medicine are solely appropriate to be prescribed to sufferers who’re severely overweight. 

‘This is as a result of medical trials have solely been undertaken in these sufferers, so the results on sufferers who should not have this degree of chubby or weight problems are unclear.’

Dr Cork stated: ‘These medicine ought to solely be taken beneath the steering of a doctor. 

‘There are necessary dosing regimens that need to be undertaken to ensure that sufferers to have the ability to tolerate the unwanted side effects of those medicine, which might not be adhered to if purchased on-line. 

‘There are uncommon incidences of life threatening problems equivalent to pancreatitis that have to be monitored.

He added: ‘It’s comprehensible that individuals who battle with their weight will attain out to any efficient remedies that turn into accessible, notably when the edge for accessing them via the NHS are fairly excessive. 

‘But it’s necessary to grasp the dangers related to taking these medicines with out the supervision of medical professionals.’  

Professor Naveed Sattar, a diabetes knowledgeable on the University of Glasgow, instructed MailOnline that there’s not but sufficient information to point out whether or not Ozempic will stop continual sickness amongst folks with out diabetes.

But research counsel that it reduces the chance of coronary heart illness and strokes amongst diabetics, he famous. 

And if folks keep a decrease weight than they’d in any other case be, as a result of drug’s appetite-suppressing impact, then the dangers of circumstances linked to being chubby, equivalent to diabetes or osteoarthritis, ‘will likely be significantly lowered’, Professor Sattar stated. 

He added: ‘[Ozempic] must also assist folks keep higher vitality ranges and psychological well being in comparisons to being a number of kilograms heavier in weight. 

‘Of course, these medicine are costly and we want long run information to reassure on security however they may assist folks. 

‘Ideally, nonetheless, we have to alter the obesogenic surroundings to assist folks placing on weight within the first place as we can not reverse the weight problems epidemic by medicine or surgical procedure alone.’ 

Three in 10 Brits and a 3rd of Americans are overweight, which raises the chance of sort 2 diabetes, some cancers, coronary heart illness and stroke. 

Targeted at these teams, weight reduction medicine may increase well being and ease stress on healthcare methods.

Diet capsules have beforehand stoke controversy after hundreds of thousands turned to ‘miracle’ urge for food suppressants fenfluramine and phentermine. But the medicine broken the guts.

Other weight reduction medicine sibutramine and rimonabant. The former prompted coronary heart injury, psychosis and suicidal ideas, whereas the latter left sufferers with despair. 

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