Health & Lifestyle

Antidepressants can numb enjoyment in addition to ache, scientists say 

Antidepressants can numb enjoyment in addition to ache by making sufferers really feel emotionally uninteresting, scientists say

  • Selective serotonin reuptake inhibitors (SSRIS) trigger ‘blunting’ of enjoyment
  • They goal serotonin and take away emotional ache but in addition some enjoyment
  • ‘Blunting’ may have an effect on between 40 and 60 per cent of sufferers taking SSRIs 

Antidepressants could make sufferers really feel emotionally uninteresting, based on scientists.

One class of antidepressants, selective serotonin reuptake inhibitors (SSRIs), targets serotonin, the ‘feel-good’ chemical that carries messages between nerve cells within the mind.

A SSRI side-effect is ‘blunting’, the place sufferers say they can’t reply with the extent of enjoyment they usually would.

Professor Barbara Sahakian, of the University of Cambridge, is a senior creator on the examine of SSRI side-effects.

Antidepressants can make patients feel emotionally dull, according to scientists (file image)

Antidepressants could make sufferers really feel emotionally uninteresting, based on scientists (file picture)

A SSRI side-effect is ‘blunting’, where patients say they cannot respond with the level of enjoyment they normally would (file image)

A SSRI side-effect is ‘blunting’, the place sufferers say they can’t reply with the extent of enjoyment they usually would (file picture)

She stated: ‘They take away a number of the emotional ache that individuals who expertise despair really feel, however, sadly, evidently in addition they take away a number of the enjoyment.’

Between 40 and 60 per cent of sufferers taking SSRIs are thought to expertise blunting. 

The examine, printed in Neuropsychopharmacology, was made up of 66 volunteers.

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