Tragic Details About Giuliana Rancic

One reason why “Giuliana & Bill” won over so many fans was Giuliana Rancic’s vulnerability and transparency when it came to showing her fertility struggles (and later, her cancer diagnosis). Though discussing things like miscarriage and IVF treatments have now become a TV staple, the topics were not as heavily discussed a decade ago. So, Rancic and her husband’s willingness to share their story resonated with many, particularly those facing conception issues themselves. 

Rancic has said she felt “blindsided” by her infertility, as she had misconceptions about fertility when she began trying to conceive at age 33. “My career was thriving, I had a wonderful partner, I was healthy — running six miles a day. I felt amazing. I felt strong. I certainly did not feel old. I still had plenty of time to have kids. Right?!” she recalls thinking.

Things did not go according to plan for the couple, who went on to experience numerous heartbreaks during their four years of trying to get pregnant. Their first IVF cycle ended in miscarriage, while the second one did not take (on her third attempt, a pre-IVF mammogram found cancer). In 2012, Rancic told Health.com (via CNN) that the second round was actually more painful than the first, miscarriage and all. “That was the biggest kick in the stomach, because I just could not believe you go through so much to get those eggs and put them in, and when the doctor calls you, to hear, ‘Oh, sorry, it didn’t work.’ That was the most shocking,” she confessed.